Table 5.
Clinical characterisation of severe dengue by age group among males
| Study population | Children | Adolescents | Adults | Elderly | |||||
|---|---|---|---|---|---|---|---|---|---|
| Clinical manifestation | n/N (%) | n/N (%) | P value | n/N (%) | P value | n/N (%) | P value | n/N (%) | P value |
| Any sign of haemorrhage | 180/350 (51·4) | 11/16 (68·8) | 0·16 | 64/105 (61·0) | 0·02* | 86/184 (46·7) | 0·07 | 19/45 (42·2) | 0·19 |
| Epistaxis | 18/176 (10·2) | 2/11 (18·2) | 0·31 | 7/62 (11·3) | 0·73 | 7/84 (8·3) | 0·43 | 2/19 (10·5) | 1·00 |
| Haematuria | 28/174 (16·1) | 0/11 (0) | 0·22 | 9/61 (14·8) | 0·72 | 12/83 (14·5) | 0·58 | 7/19 (36·8) | <0·01* |
| Gingival bleeding | 16/175 (9·1) | 1/11 (9·1) | 1·0 | 9/62 (14·5) | 0·07 | 6/83 (7·2) | 0·40 | 0/19 (0) | 0·23 |
| Gastrointestinal bleeding | 10/175 (5·7) | 2/11 (18·2) | 0·12 | 3/62 (4·8) | 1·0 | 4/83 (4·8) | 0·75 | 1/19 (5·3) | 1·0 |
| Petechiae | 56/176 (31·8) | 5/11 (45·5) | 0·32 | 19/62 (30·6) | 0·81 | 25/84 (29·8) | 0·58 | 7/19 (36·8) | 0·62 |
| Positive tourniquet test | 98/175 (56·0) | 7/11 (63·6) | 0·76 | 38/61 (62·3) | 0·22 | 48/84 (57·1) | 0·77 | 5/19 (26·3) | <0·01* |
| Any signs of plasma leakage | 123/324 (38·0) | 10/16 (62·5) | 0·04* | 52/99 (52·5) | <0·01* | 47/167 (28·1) | <0·01* | 14/42 (33·3) | 0·51 |
| Haemoconcentration | 67/324 (20·7) | 6/16 (37·5) | 0·09 | 24/99 (24·2) | 0·29 | 30/167 (18·0) | 0·21 | 7/42 (16·7) | 0·49 |
| Cavity effusion | 44/324 (13·6) | 4/16 (25·0) | 0·25 | 22/99 (22·2) | <0·01* | 13/167 (7·8) | <0·01* | 5/42 (11·9) | 0·73 |
| Hypoproteinaemia | 12/324 (3·7) | 0/16 (0) | 1·0 | 6/99 (6·1) | 0·14 | 4/167 (2·4) | 0·25 | 2/42 (4·8) | 0·66 |
| Any neurological disorders | 7/379 (1·8) | 0/16 (0) | 1·0 | 2/110 (1·8) | 1·0 | 5/202 (2·5) | 0·46 | 0/51 (0) | 0·60 |
| Any cardiac disorders | 0/379 (0) | 0/16 (0) | 1·0 | 0/110(0) | 1·0 | 0/202 (0) | 0·47 | 1/51 (2·0) | 0·14 |
n/N, Number of patients with the condition/number of patients with data available.
*
Significant P value by using χ2 test.