Figure 5.

SIA‐αTSLs combined with GM‐CSF exhibited enhanced antitumor efficiency in CT26 tumor‐bearing mice. a) Schedule of in vivo administration approach. The mice were treated with different formulations and some groups were irradiated with 808 nm laser of 1.0 W cm⁻² for 5 min. b) Body weight, c) average tumor growth curves, and d) individual tumor growth curves after intravenous injection with NS, αTSLs, Abemaciclib, A‐αTSLs, SI‐αTSLs, SI‐αTSLs+L, SIA‐αTSLs, SIA‐αTSLs+L, GM‐CSF(GC), and GC+SIA‐αTSLs+L. “S” represents SPIONs, “I” represents IR780, “A” represents Abemaciclib. e) Tumor weight and f) tumor photos at the endpoint. Data were shown as mean ± SD (n  = 6). *p < 0.05, **p < 0.01, and ***p < 0.001. g) Immunohistochemical images of the tumor tissues.