Table 2.

Multivariable analysis of OS based on LASSO and random forest.

Variables	HR	95% CI	P
LASSO
Age	1.032	1.022-1.042	<0.001
WBC	1.028	1.017-1.040	<0.001
HB	0.988	0.983-0.993	<0.001
CNS involvement	2.241	1.636-3.068	<0.001
Gender	0.659	0.524-0.829	<0.001
Ann Arbor stage	1.644	1.286-2.100	<0.001
Random forest
Age	1.031	1.021-1.041	<0.001
WBC	1.031	1.020-1.041	<0.001
HB	0.988	0.983-0.994	<0.001
CNS involvement	1.992	1.462-2.715	<0.001
ALB	0.984	0.969-0.999	0.038
ECOG	1.295	1.011-1.659	0.040