Table 3.
Parameter | Scenario | Value | Comments |
---|---|---|---|
Compliance parameters (PV, PST, PC) | 1 | 100% (baseline) | To assess the effect of reduced compliance. If 100% compliance is not observed, the waiting period is assumed to be 1 day |
2 | 99% | ||
3 | 90% | ||
4 | 80% | ||
Annual number of imports (Naqs and Nusfj) | 1 | Baseline | To assess the effect of an increased level of importation |
2 | Twofold increase | ||
3 | Threefold increase | ||
4 | Fivefold increase | ||
Probability that the animal is incubating rabies (PI,s) | 1 | Baseline | To assess the effect of an increased number of rabies cases in all exporting countries |
2 | Twofold increase | ||
3 | Fivefold increase | ||
4 | Tenfold increase | ||
Probability that a vaccinated animal is not protected (PNP) | 1 | 0·056 (baseline) | To assess the effect of a vaccine with poor efficacy being used in the exporting country |
2 | 0·1 | ||
3 | 0·2 | ||
4 | 0·5 | ||
1 | 0·056 (two-time vaccination) | To assess the effect of the required number of rabies vaccination being reduced due to policy amendment | |
2* | 0·19 (one-time vaccination) | ||
Probability that an unprotected animal passes serological testing (PST+) | 1 | 0·031 (current regimenn) | To assess the effect of compulsory serological testing is abandoned due to policy amendment |
2 | 1 (removal of testing) | ||
Waiting period in exporting countries | 1 | 180 days (baseline) | To assess the effect if the waiting period is reduced due to policy amendment |
2 | 150 days | ||
3 | 120 days | ||
4 | 90 days | ||
5 | 60 days | ||
6 | 30 days | ||
7 | 1 day | ||
Incubation period (IP) | 1 | Lognormal (23·7, 15) (experimental infection) | To assess the effect if a different probability distribution of IP is input into the model |
2 | Lognormal (27·3, 20·2) (Tokyo epidemic) | ||
3 | Lognormal (35, 36·8) (baseline) | ||
4 | Lognormal (39·7, 41·9) (natural infection or naturally acquired cases) | ||
Waiting period and required number of vaccination | 1 | No policy amendment (baseline) | To highlight to decision makers the potential for policy amendment recommended by the authors |
2 | Recommended policy amendment: 90-day waiting period and one-time vaccination |
* The PNP for this scenario is given by .