Table 4.
Cut-off point of cycle threshold (Ct) between modified measles and other measles in a real-time reverse transcription PCR in a modified measles dominated outbreak, Yamagata, Japan, 2017
Specimen | Cut-off point, Ct | Sensitivity | Specificity | AUC (95% CI) | MeV-RNA copies per tube |
---|---|---|---|---|---|
PBMC | 33.07 | 0.72 | 0.82 | 0.78 (0.63–0.93) | 1.0 × 102 |
Throat swab | 28.95 | 0.77 | 0.82 | 0.84 (0.68–0.99) | 1.7 × 103 |
Urine | 27.34 | 0.71 | 1.00 | 0.83 (0.67–0.99) | 5.0 × 103 |
AUC, area under the curve; PBMC, peripheral blood mononuclear cells.