Table 3.
Association between total, LDL and HDL cholesterol, triglyceride values and cancer by age and sex (logistic regression models)
| Lab value | Women | Men | Age < = 60 | Age 61–70 | Age 71–80 | Age > 80 |
|---|---|---|---|---|---|---|
| Total cholesterol (mg/dl) | ||||||
| < 200 | Reference | Reference | Reference | Reference | Reference | Reference |
| 200–250 |
0.91 (0.85–0.96) p = 0.002 |
0.95 (0.90–1.00) p = 0.046 |
0.99 (0.90–1.09) p = 0.852 |
0.92 (0.85–1.00) p = 0.056 |
0.93 (0.87–0.99) p = 0.030 |
0.87 (0.80–0.95) p < 0.001 |
| > 250 |
0.88 (0.80–0.97) p = 0.008 |
0.87 (0.78–0.98) p = 0.022 |
0.96 (0.81–1.13) p = 0.598 |
0.95 (0.83–1.10) p = 0.492 |
0.88 (0.77–0.99) p = 0.035 |
0.74 (0.63–0.88) p < 0.001 |
| LDL cholesterol (mg/dl) | ||||||
| < 100 | Reference | Reference | Reference | Reference | Reference | Reference |
| 100–160 |
0.95 (0.88–1.03) p = 0.212 |
0.98 (0.92–1.04) p = 0.445 |
0.95 (0.84–1.07) p = 0.427 |
0.90 (0.81–1.00) p = 0.047 |
0.98 (0.91–1.06) p = 0.600 |
1.02 (0.93–1.12) p = 0.722 |
| > 160 |
1.03 (0.92–1.15) p = 0.616 |
0.98 (0.88–1.07) p = 0.622 |
0.99 (0.83–1.17) p = 0.901 |
0.87 (0.75–1.01) p = 0.061 |
1.02 (0.90–1.15) p = 0.793 |
1.23 (1.05–1.45) p = 0.012 |
| HDL cholesterol (mg/dl) | ||||||
| > 40 | Reference | Reference | Reference | Reference | Reference | Reference |
| 31–35 |
1.17 (1.03–1.33) p = 0.015 |
(0.94–1.07) p = 0.933 |
1.19 (1.03–1.36) p = 0.017 |
1.03 (0.91–1.15) p = 0.674 |
0.99 (0.90–1.09) p = 0.856 |
0.93 (0.82–1.07) p = 0.310 |
| < 35 |
1.56 (1.35–1.81) p < 0.001 |
1.17 (1.08–1.27) p < 0.001 |
1.43 (1.21–1.68) p < 0.001 |
1.25 (1.08–1.44) p = 0.002 |
1.12 (1.00–1.26) p = 0.061 |
1.15 (0.98–1.35) p = 0.098 |
| Triglyceride (mg/dl) | ||||||
| < 150 | Reference | Reference | Reference | Reference | Reference | Reference |
| 150–200 |
1.00 (0.95–1.07) p = 0.886 |
0.95 (0.90–1.00) p = 0.059 |
1.04 (0.93–1.15) p = 0.513 |
1.01 (0.94–1.10) p = 0.743 |
0.96 (0.89–1.02) p = 0.178 |
0.92 (0.84–1.01) p = 0.070 |
| > 200 |
1.06 (0.98–1.13) p = 0.140 |
0.94 (0.88–1.01) p = 0.051 |
0.97 (0.87–1.09) p = 0.619 |
0.97 (0.89–1.06) p = 0.473 |
1.01 (0.93–1.09) p = 0.856 |
0.98 (0.88–1.09) p = 0.723 |
Significant values are in bold
*Adjusted for diabetes, obesity and each of the lipid values (i.e. association between triglyceride and cancer was adjusted for LDL, HDL and total cholesterol, diabetes and obesity)