Table 4.
Association between total, LDL and HDL cholesterol, triglyceride values and cancer by cancer sites (logistic regression models)
| Lab value | Digestive organs N = 10,108 |
Respiratory organs N = 4958 |
Skin N = 12,568 |
Female breast N = 6132 |
Prostate N = 6710 |
Urinary tract N = 4520 |
Lymphoid and hematopoietic tissue N = 7526 |
|---|---|---|---|---|---|---|---|
| Total cholesterol (mg/dl) | |||||||
| < 200 | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| 200–250 |
0.88 (0.80–0.97) p = 0.013 |
0.87 (0.75–1.00) p = 0.043 |
0.97 (0.89–1.07) p = 0.552 |
0.90 (0.79–1.03) p = 0.131 |
1.07 (0.95–1.21) p = 0.290 |
0.91 (0.79–1.05) p = 0.209 |
0.91 (0.81–1.03) p = 0.129 |
| > 250 |
0.89 (0.74–1.06) p = 0.182 |
0.70 (0.51–0.87) p = 0.003 |
1.08 (0.92–1.27) p = 0.344 |
0.93 (0.76–1.15) p = 0.528 |
0.96 (0.75–1.23) p = 0.734 |
0.73 (0.55–0.97) p = 0.031 |
0.85 (0.69–1.05) p = 0.131 |
| LDL cholesterol (mg/dl) | |||||||
| < 100 | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| 100–160 |
1.03 (0.92–1.16) p = 0.545 |
0.94 (0.79–1.11) p = 0.437 |
1.01 (0.91–1.13) p = 0.800 |
0.95 (0.80–1.13) p = 0.560 |
1.11 (0.97–1.27) p = 0.146 |
0.92 (0.78–1.09) p = 0.378 |
0.94 (0.82–1.08) p = 0.376 |
| > 160 |
1.01 (0.84–1.20) p = 0.050 |
1.24 (0.96–1.60) p = 0.107 |
0.93 (0.79–1.09) p = 0.378 |
1.11 (0.88–1.40) p = 0.394 |
1.15 (0.92–1.45) p = 0.210 |
1.07 (0.82–1.41) p = 0.609 |
0.93 (0.75–1.14) p = 0.465 |
| HDL cholesterol (mg/dl) | |||||||
| > 40 | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| 31–35 |
0.95 (0.82–1.10) p = 0.468 |
1.25 (1.02–1.52) p = 0.029 |
1.01 (0.88–1.17) p = 0.851 |
1.19 (0.91–1.56) p = 0.208 |
0.96 (0.82–1.12) p = 0.581 |
0.95 (0.77–1.16) p = 0.593 |
1.16 (0.98–1.36) p = 0.090 |
| < 35 |
1.29 (1.08.1.54) p = 0.005 |
1.37 (1.08–1.73) p = 0.010 |
1.22 (1.03–1.43) p = 0.019 |
1.18 (0.87–1.61) p = 0.298 |
1.10 (0.90–1.34) p = 0.356 |
1.19 (0.93–1.51) p = 0.160 |
1.27 (1.04–1.54) p = 0.019 |
| Triglyceride (mg/dl) | |||||||
| < 150 | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| 150–200 |
0.98 (0.89–1.09) p = 0.718 |
1.02 (0.88–1.17) p = 0.806 |
0.93 (0.85–1.02) p = 0.135 |
1.04 (0.91–1.18) p = 0.598 |
0.90 (0.80–1.02) p = 0.093 |
0.95 (0.82–1.11) p = 0.530 |
0.90 (0.80–1.01) p = 0.080 |
| > 200 |
0.96 (0.85–1.07) p = 0.422 |
1.04 (0.88–1.22) p = 0.669 |
0.91 (0.82–1.01) p = 0.080 |
1.05 (0.90–1.23) p = 0.506 |
0.81 (0.70–0.94) p = 0.004 |
1.12 (0.94–1.32) p = 0.198 |
0.99 (0.86–1.13) p = 0.832 |
*Adjusted for diabetes, obesity and each of the lipid values (i.e. association between triglyceride and cancer was adjusted for LDL, HDL and total cholesterol, diabetes and obesity)