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. 2022 May 28;272(7):1139–1155. doi: 10.1007/s00406-022-01416-6

Table 4.

Characteristics of systematic reviews that assessed the course/progress of cognitive impairment in people with schizophrenia

Citation Databases searched Range of search year Number of included studies Sample size of studies included Domain addressed Concept addressed Quality assessment
Shah et al. (2012) –PubMed –Between 1960 and 2009 –23 studies –Sample size systematically NR –More than one domain Course of CIPWS Poor quality
Irani at al. (2010) –MEDLINE –From inception to November 30, 2007 and February 16, 2008, –43 studies

2110 PWS, 1738 HC form cross-sectional studies and

–954 PWS from longitudinal studies

–More than one domain Course and factors associated Moderate quality
Bozikas and Andreou (2011) –PubMed –Until 15 January 2010 –26 studies –Sample size is not reported systematically –More than one domain Progress and associated factors Moderate quality
Szöke et al. (2008) –MEDLINE –From 1978 to 2006 –53 studies –2476 PWS and 324 HC –General Course and associated factors Poor quality
Woodberry (2008) –PubMed –Until March 1, 2007 –18 studies –Sample size systematically NR –IQ Magnitude, and course Moderate quality
Khandaker et al. (2011) –MEDLINE–PubMed, PsycINFO and Embase –From January 1984 until February 2011 –14 studies –4396 cases and over 745,000 HC –IQ Comparison and course Moderate quality

CIPWS cognitive impairment in people with schizophrenia, HC healthy controls, NR not reported, IQ intelligence quotient, PWS people with schizophrenia