Table 5.
Characteristics of systematic reviews that assessed the association of cognitive impairment in people with schizophrenia with different factors
| Citation | Databases searched and | Range of search year | Number of Included studies | Sample size of studies included | Domain addressed | Concept addressed | Quality assessment |
|---|---|---|---|---|---|---|---|
| Allott et al. (2011) | –PsycINFO and MEDLINE | –Until 31st July 2010 | –22 studies | –Sample size systematically NR | –More than one domain | Association with functionality | Good quality |
| Christensen (2007) | –PubMed (1966), PsycINFO (1967), and Embase (1974) | –Up to 2004 | –21 studies | –Range from 30 to 118 patients: and median = 75 | –General | Association with functionality | Moderate quality |
| Fett et al. (2011) | –MEDLINE and PsycINFO | –January 1977 to August 2009 | –52 studies | –2692 people with non-affective psychosis | –More than one domain | Association with functionality | Moderate quality |
| Couture et al. (2006) | –PsycINFO and MEDLINE/ PubMed | –Range of search year is NR | –NR | –Sample size included are systematically NR | –SC | Association of SC with functionality | Poor quality |
| Rajji et al. (2014) | –MEDLINE | –1999 to June 20, 2012 | –NR | –NR | –More than one domain | Association with functionality from Long-studies | Poor quality |
| Halverson et al. (2019) | –PsycINFO, PubMed, and ProQuest PsyArXiv | –Update of Fett et al. (2011) to July 2017 | –166 studies | –12,868 PWS; 518 for correlation study | –More than one domain | Association with functionality | Good quality |
| Schmidt et al. (2011) | –MEDLINE and PsycINFO | –January 2004 and December 2010 | –15 studies | –Ranges from 26 to 178 | –More than one domain | Association with functionality | Poor quality |
| Donoghue and Doody (2012) | –PsycINFO, MEDLINE, Zetoc Embase, CINAHL, Web of Knowledge | –1980 and up until October 2010 | –21 studies | –Comorbid diagnosis of a SUD was 763, and the totals with no comorbid diagnosis was 770 | –More than one domain | Association with substance | Moderate quality |
| Yüce et al (2010) | –PubMed, PsycINFO, Scopus | –Between 1987 and March 2010 | –10 studies | –572 PWS (with and without cannabis use) | –More than one domain | Cannabis as an associated variable | Moderate quality |
| Potvin et al. (2008) | –PubMed and PsycINFO | –Until 31st August 2006 | –23 studies | –1807 PWS with/without SUD, 789 PWS + SUD and 1106 PWS | –More than one domain | Substance as an associated variable | Moderate quality |
| Coulston et al. (2007) | –MEDLINE and PsycINFO | –NR | –65 studies | –Sample size are not systematically NR | –More than one domain | Substance as an associated variable | Poor quality |
| Dominguez et al. (2009) | –MEDLINE and PsychINFO | –January 1977 to April 2008 | –58 studies | –5,009 people with non-affective psychosis | –More than one domain | Association with sx dimensions | Moderate quality |
| Nieuwenstein et al. (2001) | –Psychlit and Medline | –1980 to December 1999 | –For WCST 16, and for CPT 6 studies | –Sample size are not reported systematically | –EF and At/vigilance | Association with sx dimensions | Poor quality |
| Citation | Databases searched | Range of search year | Number of Included studies | Sample size of studies included | Domain addressed | Concept addressed | Quality assessment |
|---|---|---|---|---|---|---|---|
| Maltais et al. (2015) | –PubMed and PsycINFO | –Between 1975 and 2012 | –56 studies | –5,588 PWS | –General | Association with age | Poor quality |
| Kurtz (2011) | –PsycINFO (2010), MEDLINE (2008) | –1980 up to 2008/2010 | –20 studies | –Sample size is not systematically reported | –More than one domain | Response for treatment | Poor quality |
| Keefe et al. (1999) | –MEDLINE and Psychology Abstract | –Between 1990 and April 1998 | –15 studies | –Sample size are not reported systematically | –More than one domain | Comparison b/n typical and atypical antipsychotics | Moderate quality |
| Subotnik et al. (2020) | –PsychINFO, PubMed, and Google Scholar | –January 1, 1993 to June 30, 2018 | –123 studies | –14,932 PWS | –More than one domain | Association with insight | Poor quality |
| Nair at al. (2014) | –PubMed and Web of Science | –For insight study from 2004 until September 2012 | –72 studies for insight study, 34 studies in PWS | –5429 patients for insight study, 1821 PWS | –More than one domain | Association with insight in psychotic disorder | Moderate quality |
| Agrawal at al. (2003) | –PubMed and Web of Science | –1980 and April 2004 | –35 studies | –2354 people with psychosis | –More than one domain | Association with insight | Moderate quality |
| Cooke et al. (2005) | –PsycINFO (from1967) and MEDLINE (from 1966) | –Up to December 2004 | –45 studies | –Range is between 21 and 535 | –More than one domain | Association with insight | Poor quality |
| Reinharth et al. (2014) | –PsycINFO and MEDLINE | –Up to April 2013 | –29 studies | –4764 PWS | –More than one domain | Association with Aggressive behaviour | Moderate quality |
| Vargas et al. (2019) | –PubMed, Ovid MEDLINE, and Web of Science | –On July 28, 2018 | –23 studies | –3315 people with Psychotic | –More than one domain | Association with childhood trauma | Moderate quality |
| Dauvermann and Donohoe (2019) | –PubMed and PsycINFO | –Between 1993 and December 2017 | –21 studies | –Range b/n 28 and 659 | –More than one domain | Association with childhood trauma | Poor quality |
| Allott et al. (2018) | –PubMed and Embase | –Inception to June 2015 | –43 studies | –4647 FEP patients | –More than one domain | Association with DUP | Poor quality |
| Bora et al. (2018) | –PubMed and Scopus | –January 1980 to February 2017 | –27 studies | –3127 FEP | –More than one domain | Association with DUP | Moderate quality |
CPT continuous performance test, Long-studies longitudinal studies, NR not reported, PWS people with schizophrenia, SC social cognition, SUD substance used disorder, Sx symptom; WCST wisconsin card sorting test, At attention, DUP duration of untreated psychosis, EF executive function, FEP first Episode Psychosis, PWS people with schizophrenia