Table 2.
NEC and LOS cases shown for infants without, short (≤ 72 h), or prolonged (> 72 h) early empiric antibiotic exposure
| NO EEAE (N = 137) | SHORT EEAE (N = 802) | PROLONGED EEAE (N = 320) | |
|---|---|---|---|
| NEC, N (%) | 13 (9.5) | 60 (7.4) | 34 (10.6) |
| Surgical NEC, N (%) | 4 (3) | 23 (3) | 13 (4) |
| LOS, all pathogens, N (%) | 45 (32.8) | 266 (33.2) | 110 (34.4) |
| (1) CoNS LOS, N (%) | 26 (19.0) | 158 (19.7) | 68 (21.3) |
| (2) All non-CoNS pathogens, N (%) | 22 (16.1) | 122 (15.3) | 50 (15.6) |
| (2a) Gram-positive LOS, N (%) | 14 (10.2) | 49 (6.1) | 21 (6.6) |
| (2b) Gram-negative LOS, N (%) | 10 (7.3) | 78 (9.7) | 30 (9.4) |
AB antibiotics, CoNS coagulase-negative, EEAE early empiric antibiotic exposure, h hours, NEC necrotizing enterocolitis, LOS late-onset sepsis