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. 2022 Sep 23;13:5594. doi: 10.1038/s41467-022-33274-0

Fig. 1. Overall structure of the IR/S597-component-2 complex.

Fig. 1

a Sequences of S597 and S597-N20. The residues in S597-component-1 are marked in yellow, S597-component-2 in pink, and linker in black. The disulfide bond was indicated as red. b The 3D reconstruction of the IR dimer with two S597-N20 peptides bound. c The ribbon representation of the IR dimer with two S597-N20 peptides bound fitted into the cryo-EM map at 3.6 Å resolution. d 3D reconstructions of the IR dimer from the gray dashed line in b after forced 3D refinement. e The ribbon representations of the IR dimer from the gray dashed line in b after forced 3D refinement fitted into the cryo-EM map at 3.5 Å resolution. f Close-up view of the S597-N20. g Close-up view of the binding of S597-N20 (pink) at the FnIII-1 domain of IR (green).