Table 4.

Commonly used regimens in relapse/refractory multiple myeloma.

After 1–3 Prior Therapies	After 4 Prior Therapies
Carfilzomib, lenalidomide/pomalidomide, dexamethasone Daratumumab, bortezomib/carfilzomib, dexamethasone Daratumumab, lenalidomide/pomalidomide, dexamethasone Isatuximab-irfc, lenalidomide/pomalidomide, dexamethasone Ixazomib, lenalidomide/pomalidomide, dexamethasone Pomalidomide, bortezomib, dexamethasone Elotuzumab, bortezomib, dexamethasone Elotuzumab, lenalidomide/pomalidomide, dexamethasone	Belantamab mafodotin-blmf Selinexor, dexamethasone ± bortezomib Idecabtagene vicleucel
Other Regimens (Less Commonly Used)
Venetoclax, dexamethasone [if presence of translocation (11; 14)] High dose cyclophosphamide Bendamustine, bortezomib, dexamethasone Dexamethasone, thalidomide, cisplatin, doxorubicin, Cyclophosphamide, etoposide, bortezomib