Table 4.
GRADE Summary of Findings Table of the effects of PRP and PRF on OTM.b
| Outcome (No. of studies) | Impact | Certainty |
|---|---|---|
| PRP (first 2 months) (3) | PRP injection increases OTM during early stage (first 2 months). | ⊕⊕⊕⊕ HIGH |
| PRF (first 3 months) (5) | PRF accelerates OTM in early stages. | ⊕⊕⊕◯ MODERATEa |
a
2 studies are evaluated as having some concerns.
b
GRADE, Grading of Recommendations, Assessment, Development, and Evaluation; OTM, orthodontic tooth movement; PRF, platelet-rich fibrin; PRP, platelet-rich plasma.