Table 2.

Advantages and disadvantages of adhesive.

Adhesion mechanism	Advantages	Disadvantages
Catechol-Quinone Balance	Durable adhesiveness: hemostasis (seal to stop bleeding, chitosan); antibacterial (EPL, chitosan); antioxidant	Toxic oxidant; not easy to store
Hydrogen Bond	Reversible adhesion and not affected by the surface chemistry	Limited adhesion
Amide Bond	Injectable; in situ glue; hemostasis	Limited adhesion
Imine Bond	Injectable; in situ glue; hemostasis	Limited adhesion
Topology	Wet tissue adhesion: act on any wet material when triggered by environmental stimuli	Environmental irritation may be harmful
Static Electricity	Wet adhesion; hemostasis (BIL)	Positive charge may affect cells