Table 3.
Introduction and comparison of various natural antibacterial factors.
Classification | Antibacterial mechanism | Advantages | Disadvantages |
---|---|---|---|
Silver-zeolite | Metal ions contact sterilization and catalytic sterilization. | Strong affinity that can work both in the presence and absence of oxygen. | High cost |
Silver-phosphate | Slow-release action and photocatalytic action. | Strong adsorption function, large specific surface area, nontoxicity, stable chemical properties. | High cost |
Silver-soluble glass | Slow release of sterilization. | High chemical activity, long-term sustained-release antibacterial activity. | Easy to change color, high cost. |
Titanium dioxide | Photocatalytic antibacterial activity. | Stable chemical properties, broad spectrum of sterilization, excellent acid and alkali resistance, nontoxicity, rich raw material sources. | Difficult to sedimentation, not easy to recover, not selective of sterilization. |
Zinc oxide class | Photocatalysis, metal ion dissolution and active oxygen antibacterial. | High activity, rapid antibacterial, high safety, low cost, biocompatibility, controllable morphology. | Only under ultraviolet light with sterilization, degradation of organic matter, self-purification ability, no selectivity. |
Quaternary ammonium salt | Adsorption, penetration, film breaking. | Low cost, fast antibacterial speed. | Poor durability, large effective drug dose, easy to induce drug resistance. |
Halide amine | Contact with sterilization or release of oxidizing halogen cation. | Strong stability, broad spectrum of sterilization, high efficiency, easy degradation and low toxicity. | Cannot be directly deposited on the surface of matrix. |
Chitosan | Destroys the cell wall of bacteria and hinders their free movement. | Excellent biocompatibility, low cost, nontoxicity. | Poor water solubility |
Antimicrobial peptides | Disrupt bacterial membranes and inactivate nucleic acids and cytoplasmic proteins. | High efficiency, broad-spectrum of sterilization, high killing potency, minimum risk for drug resistance. | Poor proteolytic stability, high toxicity toward mammalian cells. |
Plant extracts | Rupture of the bacterial biofilm by electrostatic interaction | Controllable release of antibacterial agents, prolonged effects, positive effects on growth factors and collagen deposition. | Poor durability |
Algae and mushroom extracts | Product targeted secondary metabolites | Broad-spectrum of sterilization, excellent antibacterial activity. | Poor anti-fungi activity, limited extraction solvent. |