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. 2022 May 28;30(8):1065–1078. doi: 10.1016/j.jsps.2022.05.011

Fig. 1.

Fig. 1

Human mitochondrial DNA. The human mitochondrial genome is organized as double-stranded a light (inner) and a heavy (outer) circular molecule containing 37 genes. 13 of these genes encode one polypeptide subunit, which is involved in the regulation of respiratory chain (RC), while the remaining 24 are necessary for RNA translation mechanism, 2 for making molecules called ribosomal RNAs (rRNAs) and 22 for transfer RNAs (tRNAs). Created with Biorender.com.