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. 2022 Sep 24;27:217–229. doi: 10.1016/j.omtm.2022.09.007

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Transcriptomic changes observed in the frontal cortex of severe COVID and AD brains

(A) Mean diff plot showing significantly upregulated (red) and downregulated (green) genes in AD brains versus control brains. (B) MA plot showing significantly upregulated (red) and downregulated (green) genes in COVID-19 versus control brains. (C) Differentially expressed genes in each dataset sorted into Gene Ontology (GO) pathways (Panther-db). Pathways containing at least 10 differentially expressed genes from each dataset are shown. Please see supplemental information for complete gene list.