TABLE 3.
Major lung findings on different MRI sequences
| Variable | Total positives | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy | Kappa | P Value |
|---|---|---|---|---|---|---|---|---|
| GGOs | ||||||||
| Overall | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 HASTE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 BLADE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T1 VIBE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| TRUFI | 20 (80.0%) | 83.3% (63-95) | 100.0% (3-100) | 100.0% (83-100) | 20.0% (1-72) | 84.0% (64-95) | 0.29 | 0.041 |
| STIR | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| Consolidation | ||||||||
| Overall | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 HASTE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 BLADE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T1 VIBE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| TRUFI | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| STIR | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| Septal Thickening/Reticulations | ||||||||
| Overall | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 HASTE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 BLADE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| T1 VIBE | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| TRUFI | 18 (72.0%) | 75.0% (53-90) | 100.0% (3-100) | 100.0% (81-100) | 14.3% (0-58) | 76.0% (55-91) | 0.19 | 0.102 |
| STIR | 24 (96.0%) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 100.0% (3-100) | 100.0% (86-100) | 1 | <0.001 |
| Bronchial dilatation and subpleural multicystic changes | ||||||||
| Overall | 14 (56.0%) | 88.9% (68-100) | 100.0% (29-100) | 100.0% (84-100) | 81.8% (19-99) | 92.6% (80-100) | 0.84 | 0.001 |
| T2 HASTE | 11 (44.0%) | 76.2% (55-97) | 100.0% (29-100) | 100.0% (82-100) | 64.3% (12-88) | 83.3% (66-97) | 0.6 | 0.001 |
| T2 BLADE | 14 (56.0%) | 88.9% (68-100) | 100.0% (29-100) | 100.0% (84-100) | 81.8% (19-99) | 92.6% (80-100) | 0.84 | 0.001 |
| T1 VIBE | 14 (56.0%) | 88.9% (68-100) | 100.0% (29-100) | 100.0% (84-100) | 81.8% (19-99) | 92.6% (80-100) | 0.84 | 0.001 |
| TRUFI | 3 (12.0%) | 13.6% (3-35) | 100.0% (29-100) | 100.0% (29-100) | 13.6% (3-35) | 24.0% (9-45) | 0.04 | 0.495 |
| STIR | 3 (12.0%) | 13.6% (3-35) | 100.0% (29-100) | 100.0% (29-100) | 13.6% (3-35) | 24.0% (9-45) | 0.04 | 0.495 |
| Parenchymal Bands | ||||||||
| Overall | 13 (52.0%) | 92.9% (66-100) | 100.0% (72-100) | 100.0% (75-100) | 91.7% (62-100) | 96.0% (80-100) | 0.92 | <0.001 |
| T2 HASTE | 13 (52.0%) | 92.9% (66-100) | 100.0% (72-100) | 100.0% (75-100) | 91.7% (62-100) | 96.0% (80-100) | 0.92 | <0.001 |
| T2 BLADE | 13 (52.0%) | 92.9% (66-100) | 100.0% (72-100) | 100.0% (75-100) | 91.7% (62-100) | 96.0% (80-100) | 0.92 | <0.001 |
| T1 VIBE | 13 (52.0%) | 92.9% (66-100) | 100.0% (72-100) | 100.0% (75-100) | 91.7% (62-100) | 96.0% (80-100) | 0.92 | <0.001 |
| TRUFI | 12 (48.0%) | 85.7% (57-98) | 100.0% (72-100) | 100.0% (74-100) | 84.6% (55-98) | 92.0% (74-99) | 0.84 | <0.001 |
| STIR | 13 (52.0%) | 92.9% (66-100) | 100.0% (72-100) | 100.0% (75-100) | 91.7% (62-100) | 96.0% (80-100) | 0.92 | <0.001 |
| Crazy paving | ||||||||
| Overall | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 HASTE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 BLADE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| T1 VIBE | 4 (16.0%) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (40-100) | 100.0% (84-100) | 100.0% (86-100) | 1 | <0.001 |
| TRUFI | 1 (4.0%) | 25.0% (1-81) | 100.0% (84-100) | 100.0% (3-100) | 87.5% (68-97) | 88.0% (69-97) | 0.36 | 0.019 |
| STIR | 2 (8.0%) | 50.0% (7-93) | 100.0% (84-100) | 100.0% (16-100) | 91.3% (72-99) | 92.0% (74-99) | 0.63 | <0.001 |
| Pleural thickening | ||||||||
| Overall | 8 (32.0%) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 HASTE | 8 (32.0%) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (86-100) | 1 | <0.001 |
| T2 BLADE | 8 (32.0%) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (86-100) | 1 | <0.001 |
| T1 VIBE | 8 (32.0%) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (86-100) | 1 | <0.001 |
| TRUFI | 7 (28.0%) | 87.5% (47-100) | 100.0% (80-100) | 100.0% (59-100) | 94.4% (73-100) | 96.0% (80-100) | 0.9 | <0.001 |
| STIR | 8 (32.0%) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (63-100) | 100.0% (80-100) | 100.0% (86-100) | 1 | <0.001 |
BLADE, proprietary name for periodically rotated overlapping parallel lines with enhanced reconstruction [PROPELLER]; GGOs, ground glass opacities; HASTE, Half-fourier acquisition single-shot Turbo Spin-Echo; NPV, negative predictive value; PPV, positive predictive value; SpO2, saturation of peripheral oxygen; STIR, short tau inversion recovery; TRUFI, true fast imaging with steady state free precession; VIBE, volume interpolated breath-hold examination.