Table 4.
Univariate analysis of iPFS
| Parameter | iPFS(m) | P | Parameter | iPFS(m) | P |
|---|---|---|---|---|---|
| Sex | 0.538 | Number of BMs | 0.490 | ||
| Female | 21.3 | 1 | 27.5 | ||
| Male | 24.0 | 2–4 | 20.3 | ||
| Age, years | 0.129 | BM size, Dmax(cm) | 0.008 | ||
| ≤ 50 | 31.5 | ≤ 3 | 27.9 | ||
| ≥ 51 | 20.3 | > 3 | 18.2 | ||
| Smoking history | 0.501 | Primary disease control | 0.880 | ||
| No | 20.7 | Yes | 21.3 | ||
| Yes | 21.3 | No | 24.0 | ||
| KPS scores | 0.998 | EMs | 0.226 | ||
| ≥ 90 | 21.5 | No | 27.9 | ||
| ≤ 80 | 21.3 | Yes | 20.0 | ||
| Tumor histology | 0.168 | Concurrent chemotherapy | 0.407 | ||
| SCC | 22.2 | Yes | 21.3 | ||
| Adenocarcinoma | 20.7 | No | 21.3 | ||
| Thoracic operation | 0.020 | TT after BMs | 0.065 | ||
| Yes | 30.7 | Yes | 26.5 | ||
| No | 18.8 | No | 20.3 | ||
| Initial treatment of BMs | 0.234 | GPA scores | 0.108 | ||
| Yes | 27.9 | 0.5–1.5 | 18.8 | ||
| No | 36.4 | 2–2.5 | 19.7 | ||
| Neurologic symptoms | < 0.00 | ≥ 3 | 31.5 | ||
| No | 30.7 | ||||
| Yes | 17.6 | ||||
| RPA class | 0.009 | ||||
| 1 | 33.5 | ||||
| 2 | 19.7 |