Table 6.
The main toxicity attributed to intracranial radiotherapy
| Toxicity | Total (N = 156) | LINAC-SRS (N = 77) | WBRT (N = 44) | WBRT + RTB (N = 35) | P |
|---|---|---|---|---|---|
| Nervous system (encephaledema, memory and cognitive decline N (%) | 32 (20.5) | 16 (20.77) | 8 (18.18)a | 8 (22.86)a | 0.108 |
| Cutaneous radiation reaction N (%) | 48 (30.8) | 28 (36.36) | 6 (13.64) | 14 (40.00) | 0.156 |
| Systemic toxicityb N (%) | 6 (3.85) | 3 (3.90) | 2 (4.55) | 1 (2.86) | 0.738 |
aThere was one case of grade 2 toxicity
bThe most common systemic toxicities were digestive system side-effect and myelosuppression. LINAC-SRS stereotactic radiotherapy using linear accelerators, WBRT whole-brain radiotherapy, WBRT + RTB whole-brain radiotherapy plus radiotherapy boost