Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 17;50(17):9663–9674. doi: 10.1093/nar/gkac792

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Structural consequences of the engineered mutations. Panels (A) and (B) show the active sites of Kod-RI and Kod-RSGA, respectively, highlighting the interactions of the pTNA backbone with residues 606 and Y594. Panels (C), (D) and (E) show an overlay of the engineered mutations in Kod-RI (green) and Kod-RSGA (blue). The α15 helix of the finger subdomain (yellow) and the β27 sheet and the loop containing position 723 in the thumb subdomain (cyan) are highlighted.