Table 1.
Patient Characteristics
| Non-CAD | CAD | |
|---|---|---|
| Total Samples | 101 | 72 |
| Gender | ||
| F (% of total) | 70 (69.3) | 55 (76.4) |
| M (% of total) | 30 (29.7) | 17 (23.6) |
| Unknown (% of total) | 1 (0.99) | |
| Age | ||
| Years | 48.9 ± 14.6 | 65.6 ± 10.0* |
| Race/Ethnicity | ||
| AA | 12 | 6 |
| Cauc | 83 | 59 |
| Hisp | 4 | 2 |
| Asian | 1 | 1 |
| Unknow | 1 | 4 |
| Underlying Diseases/Risk Factors | ||
| Coronary artery disease | 0 | 72 |
| Tobacco | 9 | 19 |
| Hypertension | 19 | 55 |
| Hypercholesterolemia | 14 | 49 |
| Congestive heart failure | 5 | 8 |
| Myocardial Infarction | 3 | 13 |
| Sample Usage Breakdown | ||
| Isolated vessel peparations# | 79 | 43 |
| Molecular work& | 33 | 33 |
Mean ± SD. * P < 0.05 vs. non-CAD.
CAD, coronary artery disease; HTN, hypertension; AA, African-American; Cauc, Caucasian; Hisp, Hispanic.
# Total number of vessels used in each category and not the total number of tissues (some tissues were used for multiple experiments). All IHC staining was performed in a subset of same tissues as functional studdies.
& Total number of tissues used in each category and is a sum of LV tissue and isolated microvessels.
Some samples were used for molecular and isolated vessel preparations in parallel.