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. 2022 Sep 3;3(5):zqac043. doi: 10.1093/function/zqac043

Table 3.

Changes in Gene Expression in Isolated Microvesses From Subjects With CAD vs. Non-CAD Diagniosis

Atrial Adipose Total
Both Genders Male Female Both Genders Male Female Both Genders Male Female
PGC1α Non-CAD 1.00 ± 0.79 1.00 ± 0.71 1.00 ± 0.94 1.00 ± 0.38 1.00 ± 0.37 1.00 ± 0.44 1.00 ± 0.70 1.00 ± 0.65 1.00 ± 0.81
CAD 0.66 ± 0.62 1.52 ± 1.03 0.26 ± 0.25$ 0.89 ± 0.36 0.62 ± 0.28 0.98& 0.73 ± 0.57 1.05 ± 0.58 0.35 ± 0.33
CAT Non-CAD 1.00 ± 0.36 1.00 ± 0.24 1.00 ± 0.54 1.00 ± 0.43 1.00 ± 0.31 1.00 ± 0.52 1.00 ± 0.39 1.00 ± 0.26 1.00 ± 0.53
CAD 0.97 ± 0.42 1.03 ± 0.35 0.80 ± 0.35 0.97 ± 0.38 1.28 ± 0.46 0.70& 0.97 ± 0.41 1.07 ± 0.40 0.78 ± 0.32
SOD2 Non-CAD 1.00 ± 0.53 1.00 ± 0.59 1.00 ± 0.64 1.00 ± 0.48 1.00 ± 0.06 1.00 ± 0.50 1.00 ± 0.51 1.00 ± 0.52 1.00 ± 0.59
CAD 0.61 ± 0.55* 1.49 ± 1.75 0.43 ± 0.27* 0.77 ± 0.38* 0.44 ± 0.29* 0.94& 0.66 ± 0.51* 0.75 ± 0.59 0.50 ± 0.31*
PARP1 Non-CAD 1.00 ± 0.37 1.00 ± 0.16 1.00 ± 0.56 1.00 ± 0.57 1.00 ± 0.38 1.00 ± 0.74 1.00 ± 0.45 1.00 ± 0.24 1.00 ± 0.64
CAD 0.85 ± 0.31 0.97 ± 0.33 0.73 ± 0.38 0.90 ± 0.29 0.99 ± 0.35 0.75& 0.86 ± 0.30 0.98 ± 0.34 0.73 ± 0.36
OGG1 Non-CAD 1.00 ± 0.61 1.00 ± 0.59 1.00 ± 0.67 1.00 ± 0.37 1.00 ± 0.22 1.00 ± 0.14 1.00 ± 0.54 1.00 ± 0.52 1.00 ± 0.55
CAD 0.79 ± 0.33 1.23 ± 1.07 0.87 ± 0.45 0.87 ± 0.47 0.62 ± 0.43 0.90& 0.78 ± 0.41 1.02 ± 0.95 0.87 ± 0.42
SIRT3 Non-CAD 1.00 ± 0.51 1.00 ± 0.32 1.00 ± 0.46 1.00 ± 0.54 1.00 ± 0.24 1.00 ± 0.70 1.00 ± 0.52 1.00 ± 0.31 1.00 ± 0.57
CAD 0.87 ± 0.46 1.00 ± 0.45 0.73 ± 0.29 1.11 ± 0.62 1.17 ± 0.64 0.87& 0.95 ± 0.53 1.04 ± 0.54 0.75 ± 0.27

Data presented as fold change to non-CAD mean ± SD; N = 4–17.

& N = 1 (not statistical evaluation possible) * P < 0.05 unpaired t-test; $P < 0.1 unpaired t-test.