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. 2022 Aug 10;135(14):1759–1761. doi: 10.1097/CM9.0000000000002166

Figure 1.

Figure 1

hsa_circ_0056856 as a biomarker for disease severity in psoriasis. (A) The expression profiles of selected circRNAs in serum between 20 psoriasis patients and 20 HCs by RT-qPCR validation. (B) The ROC curve of hsa_circ_0056856 was calculated based on the −ΔCt value in serum from 100 psoriasis patients and 50 HCs. (C) Correlation between serum levels of hsa_circ_0056856 and PASI scores in 100 psoriasis patients. (D) hsa_circ_0056856 expression was measured before and after 7 to 8 weeks of treatment in 30 psoriasis patients by RT-qPCR. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001. circRNAs: Circular RNAs; HCs: Healthy controls; PASI: Psoriasis area and severity index; ROC: Receiver operating characteristic; RT-qPCR: Real-time reverse transcription quantitative polymerase chain reaction.