TABLE 2.

Pairwise sequence alignments (percent identities) of H. pylori AhpC with AhpC homologues from other organisms

Organisma	Eubacteria						Archaeon, M. jannaschii (anaerobic)	Eukaryota (aerobic)
	H. pylori (microaerophilic)	Aerobic		Anaerobic				Yeast		C. elegans	Human
		M. tuberculosis	Synechocystis	C. pasteurianum	S. mutans	S. typhimurium		1-Cys S. cerevisiae	2-Cys S. cerevisiae		1-Cys H. sapiens	2-Cys H. sapiens
H. pylori	100	41	46	39	34	32	32	30	46	47	27	45
M. tuberculosis		100	37	38	32	33	26	32	36	35	32	39
Synechocystis			100	51	36	35	34	29	47	55	26	57
C. pasteurianum				100	32	34	38	32	50	53	30	52
S. mutans					100	62	27	23	34	37	22	36
S. typhimurium						100	33	30	31	37	27	37
M. jannaschii							100	45	33	36	41	40
1-Cys S. cerevisiae								100	29	31	48	34
2-Cys S. cerevisiae									100	66	28	60
C. elegans										100	29	74
1-Cys H. sapiens											100	31
2-Cys H. sapiens												100

^aThe accession numbers (National Center for Biotechnology Information database) of the sequences are as follows: AhpC of H. pylori, P21762; open reading frame C of Clostridium pasteurianum, P23161; AhpC of Streptococcus mutans, BAA25695; AhpC of Salmonella typhimurium, P19479; AhpC of Mycobacterium tuberculosis, CAB03768; SLL0755 of Syechocystis sp. strain PCC6803, Q55624; AhpC of Methanococcus jannaschii, AAB98731; Prx1 of Saccharomyces cerevisiae, CAA80784; TSA-I (type Iα TPx) of S. cerevisiae, P34760; AhpC/TSA of Caenorhabditis elegans, AAA79342; Prx (hORF6) of Homo sapiens, BAA03496; proliferation-associated protein TPx2 of H. sapiens, Q06830.