Table 1.
AP-2γ level | Type of BC | Outcomes | Reference |
---|---|---|---|
↑ | ERα-positive and endocrine therapy-treated patients | Disease-free survival↓ and overall survival after 10 yr↓ | [28,29] |
↑ | ERα-positive with fulvestrant-treated patients | Response to fulvestrant treatment↓ | [30] |
↑(with Wwox↓) | Tamoxifen-resistant patients | Response to tamoxifen↓ | [31,32] |
↑(with CD44↓) | Patients with basal-derived breast cancer | Reaching pathologic complete response upon neoadjuvant chemotherapy↑ | [33] |
AP-2γ = activator protein-2 gamma, BC = breast cancer, ER = estrogen receptor, Wwox = WW domain containing oxidoreductase.