Table 3.
Univariable and multivariable analysis of association of AdapNK cell frequency with positive total plaque volume score in CMV seropositive participants.
| Characteristic | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| RR (95% CI) | P value | RR (95% CI) | P value | |
| AdapNK cells frequency | ||||
| High (>20%) | 0.74 (0.56–0.95) | .019 | 0.75 (0.58–0.97) | .030 |
| Intermediate (4.6–20%) | 0.90 (0.72–1.14) | .410 | 0.92 (0.72–1.17) | .509 |
| Low (<4.6%) | 1.0 (ref) | 1.0 (ref) | ||
| HIV status | ||||
| Positive | 1.07 (0.81–1.40) | .620 | 1.08 (0.81–1.42) | .582 |
| Negative | 1.0 (ref) | 1.0 (ref) | ||
| Age (per 10 years increase) | 1.26 (1.09–1.45) | .001 | 1.23 (1.06–1.44) | .006 |
| High blood pressure | ||||
| Present | 1.07 (0.85–1.33) | .56 | – | – |
| Absent | 1.0 (ref) | – | – | |
| Smoking exposure (per each increase in 10 pack-years) | 1.09 (1.05–1.13) | <.001 | 1.09 (1.05–1.13) | <.001 |
| LDL-cholesterol (1 mmol/l) | 1.00 (0.91–1.11) | .888 | – | – |
| Statin use | ||||
| Yes | 1.21 (0.98–1.48) | .07 | – | – |
| No | 1.0 (ref) | – | – | |
| BMI (1 kg/m2) | 0.98 (0.96–1.01) | .36 | – | – |
RR per 10-year increase in age.
RR per 10 pack per year increase in smoking.
P values considered significant are shown in bold.
95% CI = 95% confidence intervals, AdapNK cells = adaptive NK cells, BMI, body mass index, LDL-cholesterol = low density lipoprotein cholesterol, RR = relative risk.