Fig. 1. Illustration of two modes of random-access read from a multi-resolution (pyramidal) WSI.

Different resolutions, stored in the WSI, are shown as blue planes stacked on top of each other. A lower resolution is a stored down-sampled copy of the highest resolution (baseline). Here both read modes, read_rect and read_bounds, illustrate reading a region of interest containing some tissue (magenta shape) at a desired resolution. Reading of a region which is not at a pre-computed and stored resolution within the WSI (transparent white plane with a dashed outline) results in a read via a down-sample interpolation from a level with higher resolution.