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. 2022 Sep 17;46(9):1753–1765. doi: 10.1111/acer.14917

TABLE 3.

Estimates for co‐twin serial mediation models

Somatic symptoms (N = 3079) Self‐rated health (N = 3079) Life satisfaction (N = 3079)
β 95% CI β 95% CI β 95% CI
Direct effects
AUI to YA Alc Prob (a 1) 0.27 [0.24, 0.30] 0.27 [0.24, 0.30] 0.27 [0.24, 0.30]
AUI to EM Alc Prob(a 2) 0.06 [0.03, 0.10] 0.06 [0.03, 0.10] 0.06 [0.03, 0.10]
YA Alc Prob to EM Alc Prob(d 21) 0.36 [0.32, 0.39] 0.36 [0.32, 0.39] 0.36 [0.32, 0.39]
YA Alc Prob to EM outcome (b 1) 0.03 [0.00, 0.07] 0.00 [−0.04, 0.04] −0.02 [−0.06, 0.01]
EM Alc Prob to EM outcome (b 2) 0.16 [0.12, 0.20] −0.10 [−0.14, −0.06] −0.19 [−0.22, –0.15]
AUI to EM outcome −0.03 [−0.06, 0.01] 0.01 [−0.03, 0.05] 0.01 [−0.02, 0.05]
Indirect effect
AUI via YA and EM alcohol Prob (a 1 * d 21 * b 2) 0.02 [0.01, 0.02] −0.01 [−0.014, −0.006] −0.02 [−0.02, −0.01]
Adolescent covariates
BMI to EM outcome −0.03 [−0.07, 0.00] 0.05 [−0.09, −0.02] −0.01 [−0.04, 0.03]
Cigarette use to EM outcome 0.06 [0.02, 0.09] 0.00 [−0.04, 0.04] 0.02 [−0.02, 0.05]
Sex to EM outcome −0.10 [−0.14, −0.07] 0.02 [−0.02, 0.06] −0.00 [−0.04, 0.03]
Early midlife covariates
EM Rel status to EM Outcome 0.01 [−0.03, 0.04] 0.02 [−0.01, 0.06] 0.18 [0.15, 0.21]
EM Econ Standing to EM Outcome 0.15 [0.12, 0.19] −0.16 [−0.19, −0.12] −0.27 [−0.31, −0.24]
Educational attainment
Secondary education −0.01 [−0.05, 0.03] −0.01 [−0.05, 0.03] 0.02 [−0.02, 0.06]
Vocational education −0.01 [−0.05, 0.03] 0.01 [−0.04, 0.06] 0.01 [−0.03, 0.06]
Masters or Doctorate −0.02 [−0.06, 0.02] 0.02 [−0.02, 0.07] 0.02 [−0.02, 0.07]
Employment
Stay at home −0.01 [−0.05, 0.02] 0.01 [−0.03, 0.05] 0.04 [0.01, 0.08]
Student 0.03 [−0.01, 0.06] 0.00 [−0.03, 0.04] 0.02 [−0.02, 0.05]
Unemployed 0.04 [0.00, 0.07] −0.02 [−0.06, 0.01] 0.02 [−0.02, 0.05]
EM cigarette use −0.03 [−0.07, 0.02] −0.04 [−0.08, 0.00] −0.06 [−0.10, −0.03]
EM other drug use −0.05 [−0.09, −0.02] 0.01 [−0.03, 0.05] −0.06 [−0.09, −0.03]

Note: AUI, Alcohol Use Index; YA, Young Adult; EM, Early Midlife; Alc Prob, Alcohol Problems; Rel, Relationship; Econ, Economic. Bolded values indicate p < 0.05.