Table 2.
Characteristics of the study patients after PSM.
| Characteristics | After PSM | |||
|---|---|---|---|---|
| Total (n = 1280) | APTT < 44 (n = 640) | APTT ≥ 44 (n = 640) | P value | |
| Demographics | ||||
| Age, years | 72.2 (64.0-78.7) | 72.3 (64.2-78.7) | 72.2 (63.9-78.8) | 0.672 |
| Gender, female | 425 (33.2) | 208 (32.5) | 217 (33.9) | 0.635 |
| Ethnicity, n (%) | 0.707 | |||
| White | 820 (64.1) | 401 (62.7) | 419 (65.5) | |
| Black | 33 (2.6) | 16 (2.5) | 17 (2.7) | |
| Asian | 24 (1.9) | 11 (1.7) | 13 (2.0) | |
| Hispanic | 24 (1.9) | 11 (1.7) | 13 (2.0) | |
| Other | 379 (29.6) | 201 (31.4) | 178 (27.8) | |
| Comorbidities, n (%) | ||||
| Hypertension | 876 (68.4) | 431 (67.3) | 445 (69.5) | 0.434 |
| DM | 403 (31.5) | 199 (31.1) | 204 (31.9) | 0.810 |
| Peripheral vascular disease | 202 (15.8) | 105 (16.4) | 97 (15.2) | 0.591 |
| MI | 268 (20.9) | 130 (20.3) | 138 (21.6) | 0.631 |
| CHF | 415 (32.4) | 207 (32.3) | 208 (32.5) | 0.999 |
| Chronic pulmonary disease | 185 (14.5) | 91 (14.2) | 94 (14.7) | 0.874 |
| Renal failure | 123 (9.6) | 60 (9.4) | 63 (9.8) | 0.850 |
| Liver disease | 29 (2.3) | 15 (2.3) | 14 (2.2) | 0.999 |
| Obesity | 46 (3.6) | 24 (3.8) | 22 (3.4) | 0.881 |
| 24 h vital signs | ||||
| Mean SBP, mmHg | 112.9 (106.5-121.0) | 113.1 (107.4-120.7) | 112.6 (105.5-121.1) | 0.132 |
| Mean DBP, mmHg | 56.2 (52.3-60.6) | 56.2 (52.3-60.4) | 56.1 (52.4-60.9) | 0.685 |
| Mean HR, beats/min | 84.2 (78.1-90.0) | 84.0 (78.3-89.9) | 84.3 (77.6-90.0) | 0.607 |
| Mean respiratory rate, beats/minute | 16.6 (14.9-18.8) | 16.6 (15.0-18.8) | 16.6 (14.8-18.7) | 0.680 |
| Mean temperature, °C | 36.9 (36.6-37.2) | 36.9 (36.6-37.2) | 36.8 (36.6-37.2) | 0.292 |
| Mean SpO2, % | 98.2 (97.3-99.0) | 98.2 (97.2-99.0) | 98.3 (97.3-98.9) | 0.752 |
| Laboratory parameters | ||||
| WBC, 109/L | 11.0 (8.4-14.1) | 11.1 (8.4-14.2) | 10.9 (8.3-13.9) | 0.693 |
| Hemoglobin, g/dL | 9.9 (8.7-11.2) | 10.0 (8.8-11.1) | 9.8 (8.6-11.3) | 0.830 |
| Platelet, 109/L | 150.0 (114.0-201.2) | 148.0 (117.0-194.0) | 152.0 (110.0-206.0) | 0.811 |
| Sodium, mmol/L | 137.0 (135.0-139.0) | 137.0 (135.0-139.0) | 137.0 (134.0-139.0) | 0.908 |
| Potassium, mmol/L | 4.3 (3.9-4.9) | 4.3 (3.9-4.9) | 4.2 (3.8-4.9) | 0.526 |
| Creatinine, μmol/L | 0.8 (0.7-1.1) | 0.8 (0.7-1.1) | 0.9 (0.7-1.1) | 0.092 |
| Glucose, mg/dL | 137.0 (115.0-165.0) | 138.0 (119.0-165.2) | 135.0 (113.0-164.0) | 0.070 |
| Management, n (%) | ||||
| Mechanical ventilation | 1230 (96.1) | 616 (96.2) | 614 (95.9) | 0.885 |
| CRRT | 26 (2.0) | 11 (1.7) | 15 (2.3) | 0.552 |
| Vasopressor use | 1091 (85.2) | 549 (85.8) | 542 (84.7) | 0.636 |
| Severity of illness, points | ||||
| SOFA | 5.0 (3.0-6.0) | 5.0 (3.0-6.0) | 5.0 (3.0-7.0) | 0.591 |
| SAPS II | 35.0 (29.0-42.0) | 35.0 (29.0-42.0) | 35.0 (29.0-42.2) | 0.796 |
| APTT, second | 44.0 (33.7-54.7) | 33.7 (30.0-37.2) | 54.8 (47.7-68.6) | <0.001 |
PSM: propensity score matching; DM: diabetes mellitus; MI: myocardial infarction; CHF: congestive heart failure; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; WBC: white blood cell; CRRT: continuous renal replacement therapy; SOFA: Sequential Organ Failure Assessment; SAPS II: Simplified Acute Physiology Score II; APTT: activated partial thromboplastin time.