Table 6. Role of TACE in neoadjuvant chemoembolization.

HCC: hepatocellular carcinoma; LT: liver transplantation; TACE: transarterial chemoembolization

References	Design	Subjects	Criteria for inclusion	Pre-operative/post-operative TACE	Outcome
Zhang et al. (2000) [46]	Retrospective study	1725	Patients with HCC who are going to undergo hepatectomy	Pre-operative TACE	The patients who had pre-operative TACE demonstrated five-year disease-free survival.
Choi et al. (2007) [47]	Retrospective study	273	Patients with HCC who are going to undergo resection	Pre-operative TACE	Patients who had received TACE showed survival rates of one, three, and five years - 76%, 57.7%, and 51.3%, respectively; in contrast, patients without TACE showed 20%, 53.8%, and 46.8% survival rates, respectively.
Graziadei et al. (2003) [50]	Prospective study	41	Patients with HCC who are going to undergo LT	Pre-operative	Survival rates of the patients post-LT at one, two, and five years were 98%, 98%, and 93%, respectively.