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. 2022 Sep 22;51(3):655–664. doi: 10.1007/s15010-022-01917-5

Table 2.

Coagulation profile among studied groups (COVID-19 patients vs. controls)

Patients group
(n = 106)
Control group
(n = 51)
P value
INR 2.05 ± 0.86 0.96 ± 0.07 0.44
aPPT (s) 35.22 ± 13.65 29.90 ± 12.26 0.01
Fibrinogen (g/l) 3.67 ± 1.48 3.35 ± 0.72 0.15
d-Dimer (mg/l) 14.56 ± 8.98 0.45 ± 0.11  < 0.001
Factor VIII (%) 150.41 ± 91 131.01 ± 70.77 0.19
Von Willebrand factor (%) 236.69 ± 69 127.19 ± 60.67  < 0.001
Protein C (%) 111.90 ± 42.13 108.25 ± 24.39 0.56
Protein S (%) 57.75 ± 30.14 60.45 ± 10.45 0.87
Antithrombin III (%) 106.83 ± 21.55 107.45 ± 19.28 0.86
Lupus anticoagulant-1 (s) 62.90 ± 20.94 29.82 ± 13.45 < 0.001
Lupus anticoagulant-2 (s) 50.20 ± 13.70 36.45 ± 8.23  < 0.001
LA-1/LA-2 ratio 1.23 ± 0.18 1.13 ± 0.34 0.03

Data expressed as mean (SD)

s second, INR international randomized ratio, aPPT activated partial thromboplastin time, LA lupus anticoagulant

P value was significant if  < 0.05