. 2022 Sep 12;35:10618. doi: 10.3389/ti.2022.10618

TABLE 1.

Baseline recipient, donor, and transplant factors of the study cohort, stratified by transplant type.

	SPK	SPK,P+	SPK,P-	DDKA	LDKA	p-value
	n = 10,383	n = 9,832	n = 551	n = 6,202	n = 5,673
	46.65%	44.17%	2.48%	27.86%	25.49%
Recipient factors
Age (years) ^a ^, ^b						<0.0001
18–50	84.11	84.07	84.75	47.55	62.08
>50	15.89	15.93	15.25	52.45	37.92
Gender ^a ^, ^b						<0.0001
Female	39.20	39.10	41.02	42.62	42.73
Male	60.80	60.90	58.98	57.38	57.27
Race ^a ^, ^b						<0.0001
White	65.70	65.57	68.06	57.59	78.48
Black	19.91	19.97	18.87	24.22	8.81
Hispanic	11.62	11.70	10.16	13.74	10.31
Other	2.77	2.77	2.90	4.45	2.40
BMI (kg/m²) ^a ^, ^b ^, ^c						<0.0001
<18.5	1.96	1.97	1.81	1.47	1.89
18.5–24.9	50.11	50.47	43.74	30.81	40.67
25–29.9	36.25	36.26	36.12	32.65	32.15
>30	11.53	11.16	18.15	34.76	24.55
PRA% ^a ^, ^b						<0.0001
0	70.29	70.36	68.97	54.11	58.12
1–19	12.87	12.89	12.52	13.03	11.9
20–80	12.62	12.56	13.61	16.37	10.59
>80	3.40	3.36	4.17	15.41	3.21
Missing	0.83	0.83	0.73	1.08	16.18
Dialysis time ^a ^, ^b						<0.0001
0	20.47	20.38	21.96	12.24	33.83
<24	37.73	25.52	25.59	34.41	12.06
24–60	25.52	37.93	34.3	17.28	30.79
>60	5.63	5.6	6.17	25.19	2.12
Missing	10.64	10.57	11.98	10.88	21.21
CMV ^a ^, ^b						<0.0001
D + R+	18.67	18.66	18.87	13.87	0
D-R-	12.67	12.6	13.97	9.88	0
R+	29.79	29.58	33.58	41.23	36.59
Missing	38.86	39.16	33.58	35.02	63.41
Donor factors
Age (years) ^a ^, ^b ^, ^c						<0.0001
<18	19.65	19.98	13.79	9.06	0
18–50	79.64	79.38	84.21	65.64	73.17
>50	0.71	0.64	2.00	25.30	26.83
Gender ^a ^, ^b
Female	30.14	30.19	29.22	39.62	62.10
Male	69.86	69.81	90.78	60.38	37.90
Race ^a ^, ^b						<0.0001
White	63.14	63.12	63.52	71.56	79.76
Black	18.72	18.70	19.06	12.46	7.65
Hispanic	14.32	14.31	14.52	12.98	10.17
Other	3.81	3.86	2.90	3.00	3.00
BMI (kg/m²) ^a ^, ^b ^, ^c						<0.0001
<18.5	6.45	6.43	7.99	6.9	0.93
18.5–24.9	56.93	57.30	50.27	34.15	32.22
25–29.9	29.91	29.65	34.66	30.89	40.86
>30	6.62	6.54	7.99	29.76	22.60
Hypertension ^a ^, ^b ^, ^c						<0.0001
No	95.58	95.72	93.1	73.49	97.17
Yes	4.42	4.28	6.9	26.51	2.83
Transplant factor
HLA Mismatch ^a ^, ^b						<0.0001
0	0.72	0.71	0.91	12.16	8.5
1–2	3.57	3.52	4.54	7.79	18.58
3–6	95.70	95.77	94.56	79.49	71.81
Cold ischemic time (hours) ^a ^, ^b ^, ^c						<0.0001
<12	60.59	60.91	54.81	24.83	80.2
12–24	33.81	33.51	39.2	53.92	1.23
>24	1.32	1.32	1.27	17.98	0.76
Missing	4.28	4.25	4.72	3.27	17.8

p < 0.05 for chi‐squared tests comparing differences between SPK,P+, SPK,P‐, DDKA, and LDKA groups.

p < 0.05 for chi‐squared tests comparing differences between SPK, DDKA, and LDKA groups.

p < 0.05 for chi‐squared tests comparing differences between SPK,P+ and SPK,P‐ groups.

p-value was reported for testing differences between SPK, DDKA, and LDKA groups.

BMI, body mass index; CMV, cytomegalovirus; DDKA, deceased‐donor kidney transplant alone; HLA, human leukocyte antigen; LDKA, living‐donor kidney transplant alone; PRA, panel reactive antibody; SPK, simultaneous pancreas‐kidney transplantation; SPK,P+, simultaneous pancreas‐kidney transplant recipients with a functioning pancreas graft at 3‐month post‐SPK; SPK,P‐, simultaneous pancreas‐kidney transplant recipients with loss of pancreas graft at 3‐month post‐SPK.