Table 3.

Treatments available for inherited cerebellar ataxias

Disease	Treatment
ATX–TTP (Ataxia with vitamin E deficiency)	α-tocopherol (vitamin E)
ATX–CYP27A1 (Cerebrotendinous Xanthomatosis)	Chenodeoxycholic acid, ursodeoxycholic acid, cholic acid and taurocholic acid
ATX–PHYH (Refsum’s disease)	Diet with phytanic acid restriction, plasmapheresis for acute presentation
ATX–NPC1 (Niemann–Pick disease type C1)	Miglustat
ATX–ADCK3 (ARCA2/SCAR9)	Oral supplementation of coenzyme Q10
ATX–ATM (Ataxia–telangiectasia) ERCC4 (XFE progeroid syndrome)	Avoid exposure to sun and radiations
DYT/ATX–ATP7B (Wilson’s disease)	D-penicillamine, trientine, zinc acetate/sulfate and liver transplantation in acute forms
MTTP (Abetalipoproteinemia)	Fat-soluble vitamins (vitamin A, E, D, K) low-fat diet
PxMD–SLC2A1 (GLUT1 deficiency)	Ketogenic diet and triheptanoin
PxMD–KCNA1 (Episodic ataxia type 1)	Carbamazepine
PxMD–CACNA1A (Episodic ataxia type 2)	Acetazolamide 4-aminopyridine or baclofen (useful for downbeat nystagmus treatment)