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Base case cost-effectiveness acceptability curve. The graph plots the probability that domiciliary NIV is cost-effective at various UK thresholds for willingness to pay for 1 QALY (£/QALY). Between the commonly used UK thresholds of £20 000 to £30 000 per QALY, it can be seen NIV is consistently 99%–100% likely to be cost-effective. ICER, incremental cost-effectiveness ratio; NIV, non-invasive ventilation; P, probability; QALY, quality-adjusted life year.
