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One IN dose of MVA-S(3P) diminished levels of pro-inflammatory cytokines in K18-hACE2 transgenic mice. mRNA levels of several cytokines/chemokines were detected by RT-qPCR in lungs (A) and nasal washes (B) obtained at 5 days postchallenge (n = 4/group). Mean RNA levels (in A.U.) and SEM from duplicates of each sample; relative values are referred to uninfected mice. Student’s t-test: *p < 0.05; **p < 0.005; ***p < 0.001.
