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. 2022 Sep 12;13:975886. doi: 10.3389/fgene.2022.975886

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Copyright © 2022 Fu, Kadeer, He and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The key modules and hub genes identified by WGCNA. (A,B) Sample clustering after outliers were removed in GSE117525 (A) and GSE8479 (B). (C,D) The soft-threshold power selecting processes. The β = 7 in GSE117525 (C) and β = 6 in GSE8479 (D) were selected when R² reached 0.85. (E,F) Heatmaps of the correlation between module eigengenes and age in GSE117525 (E) and GSE8479 (F). The corresponding correlations and p-values were presented. (G) The overlapped genes between the green modules. (H) The overlapped genes between the turquoise module and black module.