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. 2022 Sep 21;15:2003–2012. doi: 10.2147/CCID.S379609

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© 2022 Akaza et al.

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Alpha diversity of 16s rRNA clones in comedonal contents of inflammatory acne and on the skin surface of acne patients. The Mann–Whitney U-test was employed for a statistical analysis of the skin surface of the forehead and cheek, the comedonal contents of the T-zone and U-zone, the skin surface of the forehead and the comedonal contents of the T-zone, and the skin surface of the cheek and the comedonal contents of the U-zone. In the analysis using Faith’s phylogenetic diversity and the observed OTUs, diversities were higher in the comedonal contents of the T- and U-zones than on the skin surface of the forehead and cheek (P < 0.05); however, no significant differences were observed by the Shannon index or Pielou’s evenness index. No significant differences were found in either index on the skin surface (forehead and cheek) or in comedonal contents (T- and U-zones) between females and males.