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. 2022 Sep 21;15:2003–2012. doi: 10.2147/CCID.S379609

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© 2022 Akaza et al.

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Beta diversity (weighted UniFrac values) of 16s rRNA clones in comedonal contents of inflammatory acne and on the skin surface of acne patients. Blue, skin surface (forehead); green, skin surface (cheek); red, comedonal contents of the T-zone; orange, comedonal contents of the U-zone. Significant differences were observed between the bacterial microbiome of the comedonal contents and that on the skin surface by PERMANOVA. P value; the skin surface of the forehead versus the comedonal contents of the T-zone, <0.001; the skin surface of the cheek versus the comedonal contents of the U-zone, 0.006.