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. 2022 Sep 21;15:2003–2012. doi: 10.2147/CCID.S379609

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© 2022 Akaza et al.

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Species classifications of ITS clones in comedonal contents of inflammatory acne and on the skin surface of acne patients. The individual distribution of the main fungal species arranged in descending order of M. restricta is shown. f, Female; m, male; T, T-zone; U, U-zone. Only fungi with an average detection rate of 1% or higher are listed, and fungi with an average detection rate of less than 1% are classified as others. The Mann–Whitney U-test was employed for a statistical analysis of the skin surface of the forehead and cheek, the comedonal contents of the T-zone and U-zone, the skin surface of the forehead and the comedonal contents of the T-zone, and the skin surface of the cheek and the comedonal contents of the U-zone. No significant differences were observed between comedonal contents and the skin surface. Furthermore, no significant differences were noted in any fungus on the skin surface (forehead and cheek) or in comedonal contents (T- and U-zones) between females and males.