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. 2022 Feb 3;20(1):70–86. doi: 10.1016/j.gpb.2022.01.005

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© 2022 Beijing Institute of Genomics

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Supplementary figure S3 — Cluster 1 cells exhibited a stem-like transcriptional signature. A. Heatmap of the correlation matrix between the transcriptome of each subpopulation and cells from published datasets [43], including DLL1+ PXM, LTM, and ESM. B. Dot plot showing the relative expression levels of the activated transcription factors (CTCF, EZH2, E2F8, PBX3, MYBL2, E2F1, and TFDP1) in Cluster 1 predicted by SCENIC. C. Violin plots showing the expression levels of stemness-associated markers (CD9, CD44, ITGB1, SDC4, and ITGAV) in each cluster. D. Violin plots showing the expression levels of genes involved in mesodermal development (SCX, ZFP36L1, FOXC1, and IRX3) in each cluster.