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. 2021 Jul 15;20(1):129–146. doi: 10.1016/j.gpb.2021.01.006

Table 1.

SLM2-bound TTN transcripts/exons in the heart tissues of DCM patients

Gene Exon Transcript SLM2-bound in DCM vs. control (fold change) T statistic P value
TTN 89 205:ENST00000425332+ENST00000589042 18.614 −2.692 0.027
TTN 92 204:ENST00000425332+ENST00000589042 227.126 −2.734 0.025
TTN 103 210:ENST00000589042 44.288 −3.029 0.016
TTN 131 241:ENST00000591111+ENST00000342992+ENST00000589042+ENST00000615779 95.296 −4.139 0.003
TTN 139 181:ENST00000589042 104.234 −4.564 0.001

Note: Exons/transcripts of TTN mRNA which bound to SLM2 were identified in the heart tissues of DCM patients using RIP-seq. SLM2, Sam68-like mammalian protein 2; TTN, titin; DCM, dilated cardiomyopathy; RIP-seq, RNA immunoprecipitation followed by next-generation sequencing.