Table 1.
Gene | Exon | Transcript | SLM2-bound in DCM vs. control (fold change) | T statistic | P value |
---|---|---|---|---|---|
TTN | 89 | 205:ENST00000425332+ENST00000589042 | 18.614 | −2.692 | 0.027 |
TTN | 92 | 204:ENST00000425332+ENST00000589042 | 227.126 | −2.734 | 0.025 |
TTN | 103 | 210:ENST00000589042 | 44.288 | −3.029 | 0.016 |
TTN | 131 | 241:ENST00000591111+ENST00000342992+ENST00000589042+ENST00000615779 | 95.296 | −4.139 | 0.003 |
TTN | 139 | 181:ENST00000589042 | 104.234 | −4.564 | 0.001 |
Note: Exons/transcripts of TTN mRNA which bound to SLM2 were identified in the heart tissues of DCM patients using RIP-seq. SLM2, Sam68-like mammalian protein 2; TTN, titin; DCM, dilated cardiomyopathy; RIP-seq, RNA immunoprecipitation followed by next-generation sequencing.