Table 3.

Univariate and multivariate analysis: Tricuspid valve (TV) reintervention or tricuspid valve regurgitation (TR) deemed moderate or greater

Variable	Univariate analysis		Multivariable analysis∗
	HR (95% CI)	P value	HR (95% CI)	P value
Age	1.0 (0.9-1.0)	.07
Age <12 y	3.1 (1.3-7.4)	.01	2.7 (1.1-6.7)	.04
Male	0.9 (0.4-2.3)	.87
Previous cardiac surgery	1.0 (0.4-2.4)	.95
Age at first cardiac intervention (y)	0.9 (0.8-1.1)	.23
Genetic syndromes present	0.6 (0.1-5.0)	.67
Other cardiac malformations	0.7 (0.2-2.2)	.57
No. of previous cardiac interventions = 0	0.82 (0.32-2.5)	.82
No. of previous cardiac interventions = 1	1 (0.8-1.8)
No. of previous cardiac interventions ≥2	1.2 (0.7-3.5)
BSA	0.6 (0.3-1.1)	.09
Weight	1.0 (0.9-1.0)	.20
Diameter of TV annulus (mm)	1.0 (0.9-1.0)	.82
AS moderate or greater	0.5 (0.1-3.8)	.51
AI moderate or greater	1.8 (0.4-8.5)	.44
PR moderate or greater	1.0 (0.4-2.6)	.96
MS moderate or greater	0.7 (0.1-4.9)	.68
MR moderate or greater	8.7 (2.1-12.6)	.002	6.2 (1.5-12.8)	.01
Preoperative degree of TR†
Mild	2.3 (0.1-17)	.55
Moderate	1.7 (0.2-14)	.62
Severe	2.1 (0.3-15)	.47
RV dysfunction	0.9 (0.3-2.6)	.82
LV dysfunction‡	2.9 (0.7-8.5)	.16
Etiology of TV lesion
RV/RVOT/PA obstruction	0.9 (0.4-2.1)	.81
Right heart volume overload	1.8 (0.7-4.1)	.20
Iatrogenic lesion	0.5 (0.1-3.5)	.46
Congenital/isolated TV lesion	1.6 (0.4-7.1)	.52
Crossclamp time (per min)	1.0 (1.0-1.1)	.16
CPB time (per min)	1.0 (1.0-1.1)	.77
Repair§	0.8 (0.3-2.4)	.65

Bold values highlight statistically significant findings. HR, Hazard ratio; CI, confidence interval; BSA, body surface area; AS, aortic stenosis; AI, aortic insufficiency; PR, pulmonary regurgitation; MS, mitral stenosis; MR, mitral regurgitation; RV, right ventricle; LV, left ventricle; RVOT, right ventricular outflow tract; PA, pulmonary artery; CPB, cardiopulmonary bypass.

^∗Corrected C index = 0.62 after bootstrapping × 1000.

^†Reference category is no TR.

^‡Defined as EF <50%.

^§Reference category is replacement.