TABLE 2.
Antibody response, lymphocytes and interleukin-6 (IL-6) according to cluster assignment
| Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | Cluster 5 | Cluster 6 | |
| Subjects n (%) | 51 (20.1) | 21 (8.3) | 35 (13.8) | 15 (5.9) | 82 (32.3) | 50 (19.7) |
| Anti-SARS-CoV-2 S1 IgG antibodies pg·mL−1 # | ||||||
| Minimum | 0 | 0 | 1425 | 0 | 0 | 1958 |
| 25% | 0 | 301.9 | 2850 | 184.7 | 1317 | 2934 |
| Median | 191.7 | 2246.2 | 3013 | 877.1 | 2113 | 3074 |
| 75% | 450 | 2969.7 | 3152 | 2923.2 | 2848 | 3286 |
| Maximum | 1019.6 | 3423.5 | 3828 | 3444.7 | 3556 | 3893 |
| T-cells per mm3 ¶ | ||||||
| Minimum | 95.0 | 88.0 | 93.0 | 227 | 191.0 | 159.0 |
| 25% | 252.0 | 338.0 | 266.5 | 594 | 489.2 | 729.0 |
| Median | 372.0 | 418.0 | 343.0 | 1015 | 619.0 | 954.5 |
| 75% | 644.0 | 767.0 | 422.0 | 2010 | 743.2 | 1208.2 |
| Maximum | 1008.0 | 992.0 | 557.0 | 3662 | 1574.0 | 2650.0 |
| B-cells per mm3 ¶ | ||||||
| Minimum | 0.00 | 16.0 | 13.00 | 71.0 | 16.00 | 31.0 |
| 25% | 40.50 | 50.0 | 47.50 | 214.0 | 72.25 | 119.2 |
| Median | 56.00 | 101.0 | 67.00 | 660.0 | 103.00 | 188.0 |
| 75% | 83.00 | 129.0 | 89.50 | 973.0 | 147.00 | 262.0 |
| Maximum | 161.00 | 271.0 | 121.00 | 3097.0 | 286.00 | 467.0 |
| NK cells per mm3 ¶ | ||||||
| Minimum | 7.0 | 7.00 | 20.00 | 83.0 | 31.0 | 42.0 |
| 25% | 72.5 | 49.00 | 38.00 | 135.0 | 92.0 | 110.5 |
| Median | 113.0 | 103.00 | 56.00 | 259.0 | 125.0 | 146.0 |
| 75% | 185.5 | 131.00 | 69.50 | 399.5 | 162.8 | 202.5 |
| Maximum | 459.0 | 201.00 | 106.00 | 790.0 | 327.0 | 362.0 |
| IL-6 pg·mL−1 + | ||||||
| Minimum | 4.93 | 93.2 | 8.14 | 3.48 | 2.96 | 2.00 |
| 25% | 34.45 | 2018.0 | 24.90 | 16.55 | 16.02 | 3.692 |
| Median | 57.70 | 315.0 | 58.20 | 32.10 | 24.85 | 5.34 |
| 75% | 89.55 | 620.0 | 105.00 | 59.35 | 40.35 | 7.28 |
| Maximum | 184.0 | 1000.0 | 237.00 | 232.00 | 71.50 | 13.10 |
#: SARS-CoV-2 anti-S1 IgG antibodies were measured a median of 4 days after admission to the hospital; ¶: decreases in circulating lymphocytes were defined as the lowest T-, B- and natural killer (NK) cell absolute counts recorded after admission; +: IL-6 increase was defined as the maximal serum level recorded after admission.