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. 2022 Sep 12;13:924338. doi: 10.3389/fendo.2022.924338

Table 1.

Demographic characteristics in different subgroups.

Total Male Female P values
Children Adolescents Children Adolescents
n (%) 1097 (100) 239 (21.79) 298 (27.16) 237 (21.60) 323 (29.44)
N (%) 38600094 (100) 7468190 (19.35) 11926998 (30.90) 6947749 (18.00) 12257157 (31.75)
Age (years), mean (SD) 12.79 (3.79) 8.54 (1.64) 15.15 (2.23)c*** 8.70 (1.75)d*** 15.39 (2.10)c***,e*** <0.001a
Race/ethnicity, N (%)
Non-Hispanic White 20735553 (53.72) 4098602.3 (54.88) 6695143.3 (56.13) 3409718.6 (49.08) 6532088.6 (53.29) <0.001
Non-Hispanic Black 4470180 (11.58) 867816.9 (11.62) 1460253.9 (12.24) 766690.6 (11.04) 1375419.0 (11.22)
Mexican American 6126108 (15.87) 1141425.9 (15.28) 1776932.6 (14.90) 1423325.8 (20.49) 1784424.1 (14.56)
Other Race 7268253 (18.83) 1360345.2 (18.22) 1994668.1 (16.72) 1348013.8 (19.40) 2565225.6 (20.93)
Family PIR, N (%)
PIR<=1 9112689 (23.61) 1770793 (23.71) 2500823 (20.97) 1959315 (28.20) 2881758 (23.51) <0.001
PIR >1 29487405 (76.39) 5697398 (76.29) 9426174 (79.03) 4988434 (71.80) 9375399 (76.49)
Serum cotinine, N(%)b
<LLOD 14073182 (36.46) 2612187 (34.98) 3416099 (28.64) 3034115 (43.67) 5010780 (40.88) <0.001
>=LLOD 24526912 (63.54) 4856003 (65.02) 8510899 (71.36) 3913633 (56.33) 7246377 (59.12)
BMI category, N (%)
Normal weight 29149987 (75.52) 6856528.4 (91.81) 8807098.2 (73.84) 6262098.2 (90.13) 7224262.1 (58.94) <0.001
Overweight 5213428 (13.51) 381018.3 (5.10) 1706794.2 (14.31) 467642.4 (6.73) 2657973.5 (21.69)
Obese 4236679 (10.98) 230643.6 (3.09) 1413105.5 (11.85) 218008.2 (3.14) 2374921.8 (19.38)
Survey time period
Nov. 1 to Apr. 30 17545321 (45.45) 3559588 (47.66) 5941689 (49.82) 2951352 (42.48) 5092692 (41.55) <0.001
May 1 to Oct. 31 21054773 (54.55) 3908602 (52.34) 5985309 (50.18) 3996397 (57.52) 7164465 (58.45)
Blood collection, N (%)
Morning 16730845 (43.34) 2458553 (32.92) 5235360 (43.90) 3033536 (43.66) 6003396 (48.98) <0.001
Afternoon 14155481 (36.67) 3306334 (44.27) 4585101 (38.44) 2304349 (33.17) 3959697 (32.31)
Evening 7713768 (19.98) 1703303 (22.81) 2106537 (17.66) 1609864 (23.17) 2294064 (18.72)

Sampling weights were applied for calculation of demographic descriptive statistics and N represents the weighted sample size.

a: Age differences of four subgroups (male children, male adolescents, female children and female adolescents) were tested by Welch’s ANOVA because the four subgroups satisfy approximate symmetry and heteroscedasticity; other differences across four subgroups were tested by Chi-square test.

b: The LLOD of serum cotinine was set at 0.015 ng/mL.

c, d, and e represent the post hoc result of SNK method with the group of Male Children, Male Adolescents, and Female Children, respectively, with ***P<0.001.