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. 2022 Aug 24;36(5):1648–1659. doi: 10.1111/jvim.16525

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© 2022 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Proliferative and apoptotic features of DCH‐positive liver section of HPD cats. (A) The PCNA and phospho‐histone H3 (B) immunostainings were diffusely presented within the nucleus of hepatocytes (golden brown precipitates), indicating proliferative activity of DCH‐infected liver. (C) Cytoplasmic immunostaining of survivin was positive within the cytoplasm of hepatocytes. (D) No immunostaining of cleaved caspase‐3 was found in the DCH‐positive liver section (red precipitates). Bars indicate 170 μm