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miR-146aKO B cells have higher in vivo immunization responses to T-independent antigen than WT. (A) Primary immunization antibody response to T-independent antigen at day 28 show TNP-LPS specific antibodies vs. (B) total IgM, IgG antibodies. (C) FACS analysis of plasma cells and subsets at endpoint. n = 6-9 mice/group. All analysis used t test for respective time point comparisons; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Data represent mean ± SEM.
