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. 2022 Sep 12;9:972399. doi: 10.3389/fnut.2022.972399

Table 3.

Subgroup analysis of dietary fiber intake in glycaemic control.

Fasting plasma glucose Fasting plasma insulin
No. of studies ES
(95% CI)
Heterogeneity No. of studies ES (95% CI) Heterogeneity
P P
Country
China 16 −0.69
(−0.92, −0.45)
98.20 <0.001 14 −1.202
(−1.615, −0.789)
56.36 0.005
Iran 3 −0.66
(−3.41, 2.09)
87.44 <0.001 2 −1.172
(−2.491, 0.147)
68.96 0.073
USA 2 −0.48
(−1.15, 0.18)
90.54 0.001 1 ~ ~ ~
Other 6 −0.26
(−0.61, 0.09)
75.32 0.001 1 ~ ~ ~
Study population
Diabetics 14 −1.52
(−2.08, −0.97)
98.46 <0.001 9 −1.619
(−2.492, −0.746)
68.01 0.002
Dyslipidemia 2 −0.04
(−0.09, 0.01)
0 0.587 1 ~ ~ ~
MS 1 ~ ~ ~ 1 ~ ~ ~
Other 10 −0.13
(−0. 21, −0.05)
62.55 0.004 7 −0.980
(−1.439, −0.522)
46.17 0.084
Type of effect size
WMD 13 −0.17
(−0.28, −0.06)
80.90 <0.001 9 −1.303
(−1.616, −0.991)
38.04 0.115
SMD 2 −0.42
(−0.70, −0.13)
71.58 0.061 3 −0.588
(−0.835, −0.341)
0 0.397
MD 12 −1.20
(−1.64, −0.77)
98.63 <0.001 6 −1.947
(−2.917, −0.976)
43.95 0.112
Type of intervention
RS 6 −0.094
(−0.185, −0.004)
61.68 0.023 5 −1.618
(−2.503, −0.732)
69.02 0.012
β-glucan 4 −0.056
(−0.102, −0.011)
49.62 0.114 3 0.186
(−2.303, 2.675)
34.19 0.219
ITF 5 −2.807
(−3.741, −1.874)
99.48 <0.001 5 −1.277
(−1.672, −0.881)
0 0.811
Others 12 −0.499
(−0.831, −0.168)
83.54 <0.001 5 −0.961
(−1.872, −0.051)
69.94 0.010
Sample size
n <300 5 −0.628
(−1.181, −0.076)
73.66 0.004 5 −1.701
(−2.766, −0.636)
50.27 0.09
300 ≤ n <600 13 −0.89
(−1.23, −0.54)
98.48 <0.001 9 −1.293
(−1.934, −0.651)
54.96 0.023
n ≥ 600 9 −0.26
(−0.41, −0.13)
86.34 <0.001 4 −1.094
(−1.689, −0.500)
74.70 0.008
Dosage
n <5 6 −0.103
(−0.212, 0.006)
64.92 0.014 3 −0.186
(−2.306, 2.675)
34.19 0.219
5 ≤ n <10 7 −2.843
(−3.843, −1.843)
99.23 <0.001 6 −1.257
(−2.048, −0.465)
68.50 0.007
n ≥ 10 12 −0.161
(−0.256, −0.067)
74.06 <0.001 8 −1.448
(−2.029, −0.867)
56.31 0.025
Duration
n <7 8 −0.086
(−0.140, −0.032)
52.86 0.038 6 −0.902
(−1.218, −0.586)
0 0.457
7 ≤ n <11 13 −1.363
(−1.856, −0.869)
98.55 <0.001 11 −1.452
(−2.037, −0.867)
67.78 0.001
n ≥ 12 5 −0.175
(−0.598, 0.249)
797.52 0.001 1 ~ ~ ~
HOMA-IR HbA1c
Country
China 9 −0.490
(−0.611, −0.369)
21.31 0.254 10 −0.442
(−0.627, −0.258)
91.51 <0.001
Iran 2 −0.174
(−0.375, 0.027)
0 0.451 2 −0.293
(−0.910, 0.324)
85.60 0.008
USA 1 ~ ~ ~ 1 ~ ~ ~
Other 3 −0.245
(−0.844, 0.354)
67.05 0.048 5 −0.289
(−0.447, −0.130)
56.37 0.057
Study population
Diabetics 9 −0.522
(−0.774, 0.270)
54.78 0.024 13 −0.393
(−0.535, −0.251)
89.31 <0.001
Dyslipidemia 0 ~ ~ ~ 0 ~ ~ ~
MS 1 ~ ~ ~ 1 ~ ~ ~
Other 5 −0.348
(−0.610, −0.086)
56.80 0.055 4 −0.297
(−0.447, −0.146)
32.17 0.219
Type of effect size
WMD 6 −0.345
(−0.463, −0.228)
51.25 0.068 8 −0.361
(−0.549, −0.173)
88.13 <0.001
SMD 3 −0.618
(−0.874, −0.362)
0 0.829 2 −0.596
(−0.779, −0.412)
43.81 0.182
MD 6 −0.458
(−0.899, −0.017)
63.33 0.018 8 −0.345
(−0.489, −0.202)
71.82 0.001
Type of intervention
RS 6 −0.311
(−0.450, −0.173)
0 0.827 5 −0.225
(−0.384, −0.065)
81.69 <0.001
β-glucan 0 ~ ~ ~ 1 ~ ~ ~
ITF 3 −0.648
(−0.882, −0.415)
0 0.446 3 −0.589
(−0.730, −0.448)
38.07 0.199
Others 6 −0.507
(−0.928, −0.086)
72.86 0.002 9 −0.408
(−0.587, −0.229)
77.90 <0.001
Sample size
n <300 6 −0.347
(−0.506, −0.189)
48.15 0.086 6 −0.388
(−0.649, −0.128)
89.89 <0.001
300 ≤ n <600 5 −0.353
(−0.567, −0.139)
41.90 0.142 7 −0.312
(−0.466, −0.157)
80.40 <0.001
n ≥ 600 4 −0.483
(−0.820, −0.147)
74.96 0.007 5 −0.493
(−0.726, −0.260)
62.83 0.029
Dosage
n <5 0 ~ ~ ~ 1 ~ ~ ~
5 ≤ n <10 6 −0.653
(−0.829, −0.477)
0 0.510 6 −0.631
(−0.740, −0.521)
8.87 0.359
n ≥ 10 7 −0.324
(−0.462, −0.186)
1.02 0.416 8 −0.304
(−0.456, −0.151)
82.34 <0.001
Duration
n <7 3 −0.298
(−0.451, −0.144)
0 0.398 4 −0.196
(−0.380, −0.013)
73.43 0.010
7 ≤ n <11 10 −0.540
(−0.760, −0.320)
54.06 0.021 9 −0.474
(−0.682, −0.266)
85.80 <0.001
n ≥12 2 −0.374
(−1.762, −1.013)
64.43 0.094 4 −0.379
(−0.645, −0.113)
79.96 0.002

ES, effect size; MS, metabolic syndrome; RS, resistant starch; ITF, inulin-type fructans; WMD, weight mean difference; SMD, standardized mean difference; MD, mean difference.