Table 2.
Interpretive criteria and MIC values of CCM, CAP and antimicrobial agents tested against C. difficile strains
| Agents | Interpretation | MIC | |||||
|---|---|---|---|---|---|---|---|
| S | I | R | RT 001 | RT 126 | RT 084 | 700057 | |
| CCM (μM) | – | – | – | 256 | 256 | 128 | 128 |
| CAP (μM) | – | – | – | 256 | 256 | 128 | 128 |
| MET (μg/ml) | ≤ 8 | 16 | ≥ 32 | 1 | 0.5 | 0.5 | 0.5 |
| VAN (μg/ml) | ≤ 2 | NA | ≥ 8 | 0.5 | 0.5 | 1 | 0.5 |
| FDX (μg/ml) | ≤ 1 | > 1 | NA | 0.5 | 0.5 | 0.5 | 0.5 |
Breakpoints were defined as susceptible (S), intermediately resistant (I), or resistant (R) with reference to CLSI, EUCAST or published data. NA, not available
CCM curcumin, CAP capsaicin, MET metronidazole, VAN vancomycin, FDX fidaxomicin