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. 2022 Sep 26;14:137. doi: 10.1186/s13098-022-00907-9

Table 3.

Multivariable logistic regression of four IR surrogates and the prevalence of hypertension

Crude model Model 1 Model 2
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
TG/HDL-c
Q 1 (≤ 1.27) Ref. Ref. Ref.
Q 2 (1.27–1.90) 1.069 (1.021–1.119)  < 0.001 1.034 (0.985–1.086) 0.181 1.012 (0.938–1.092) 0.759
Q 3 (1.90–2.93) 1.096 (1.047–1.147)  < 0.001 1.034 (0.985–1.086) 0.175 0.991 (0.914–1.075) 0.825
Q 4 (≥ 2.93) 1.124 (1.074–1.176)  < 0.001 1.038 (0.989–1.090) 0.128 0.952 (0.854–1.060) 0.369
p for trend  < 0.001 0.152 0.413
TyG index
Q 1 (≤ 7.99) Ref. Ref. Ref.
Q 2 (7.99–8.37) 1.10 (1.051–1.154)  < 0.001 1.068 (1.016–1.122) 0.01 0.997 (0.905–1.056) 0.977
Q 3 (8.37–8.79) 1.175 (1.122–1.231)  < 0.001 1.090 (1.038–1.145)  < 0.001 0.995 (0.918–1.077) 0.995
Q 4 (≥ 8.79) 1.230 (1.175–1.288)  < 0.001 1.106 (1.054–1.162)  < 0.001 0.929 (0.838–1.030) 0.929
p for trend  < 0.001  < 0.001 0.319
TyG-BMI
Q 1 (≤ 173.52) Ref. Ref. Ref.
Q 2 (173.52–193.87) 1.975 (1.857–2.10)  < 0.001 1.512 (1.418–1.612)  < 0.001 1.174 (1.059–1.302) 0.002
Q 3 (193.87–216.06) 3.264 (3.080–3.458)  < 0.001 2.163 (2.035–2.229)  < 0.001 1.320 (1.176–1.483)  < 0.001
Q 4 (≥ 216.06) 5.863 (5.546–6.198)  < 0.001 3.724 (3.511–3.950)  < 0.001 1.404 (1.202–1.642)  < 0.001
p for trend  < 0.001  < 0.001  < 0.001
METS-IR
Q 1 (≤ 29.37) Ref. Ref. Ref.
Q 2 (29.37–33.21) 2.507 (1.934–2.188)  < 0.001 1.596 (1.497–1.703)  < 0.001 1.267 (1.136–1.414)  < 0.001
Q 3 (33.21–37.44) 3.520 (3.322–3.731)  < 0.001 2.357 (2.216–2.506)  < 0.001 1.489 (1.307–1.696)  < 0.001
Q 4 (≥ 37.44) 5.841 (5.523–6.178)  < 0.001 3.776 (3.555–4.011)  < 0.001 1.510 (1.262–1.807)  < 0.001
p for trend  < 0.001  < 0.001  < 0.001

OR odds ratio, CI confidence interval, Q quartile, IR insulin resistance, TG/HDL-c triglycerides/high-density lipoprotein cholesterol ratio, TyG index Triglyceride-glucose index, TyG-BMI TyG index with body mass index, METS-IR metabolic score for insulin resistance

Model 1 adjust age and gender

Model 2 adjust Model 1 + BMI (kg/m2), FPG (mmol/L), ALT(U/L), AST(U/L), BUN, Scr, smoking status (current smoker or not), drinking status (current drinker or not), family history of diabetes (Yes or No)